Statistics Colloquium: Chiara Sabatti (Stanford University)

Date: 

Monday, September 27, 2021, 12:00pm to 1:00pm

Location: 

Zoom - please contact emilie_campanelli@fas.harvard.edu for more information

Headshot of Chiara SabattiTitle:

Genetic variants across human populations and our understanding of the genetic basis of traits

Abstract:

Identifying which genetic variants influence medically relevant phenotypes is an important task both for therapeutic development and for risk prediction. In the last decade, genome wide association studies have been the most widely-used instrument to tackle this question. One challenge that they encounter is in the interplay between genetic variability and the structure of human populations. In this talk, we will focus on some opportunities that arise when one collects data from diverse populations and present statistical methods that allow us to leverage them.

The presentation will be based on joint work with M. Sesia, S. Li, Z. Ren, Y. Romano and E. Candes.