We developed a computational approach to study tumor-infiltrating immune cells and their interactions with cancer cells. Analysis of over ten thousand RNA-seq samples from the Cancer Genome Atlas (TCGA) identified strong association between immune infiltrates and patient clinical features, viral infection status, and cancer genetic alterations. We found that melanomas with high...
How can one combine a collection of estimators of a regression function into a good aggregate? In the last 15 years, this age-old question has received increasing attention within the Mathematical Statistics community. A closely related question of regression in misspecified models has been studied within Statistical Learning using the techniques of empirical processes. We outline the...